Aicar 50mg
- Dramatically increases endurance & VO2 max.
- Shifts metabolism to fat burning (even at rest).
- Improves insulin sensitivity & glucose uptake.
- Enhances mitochondrial biogenesis.
Is AICAR Safe?
Aicar 50mg has been extensively studied in human clinical trials (up to 1000 mg/day) with a favorable safety profile. At performance doses (25-100 mg/day), side effects are rare and mild — occasional flushing or nausea. Long-term safety in healthy individuals is not fully established, but no serious adverse events have been reported in research.
What is AICAR Used For?
Aicar 50mg is used to activate AMPK (the body's master metabolic switch), mimicking the effects of exercise. Originally developed for cardiac ischemia, it is now famous for dramatically increasing endurance, accelerating fat loss, and improving metabolic health in research and athletic circles.
How Does AICAR Promote Weight Loss?
Aicar 50mg activates AMPK → increases fatty acid oxidation, inhibits fat storage, and boosts mitochondrial density. Users report stubborn fat melting (especially abdominal) even without major diet changes, while preserving muscle mass.
Does AICAR Affect Muscle Growth?
Aicar 50mg is not anabolic — it does not directly build muscle like GH or AAS. However, by increasing mitochondrial density and endurance, it allows longer, more intense training sessions and better recovery, indirectly supporting hypertrophy when combined with proper training and nutrition.
How Long Does Aicar 50mg Stay in Your System?
Aicar has a plasma half-life of ~1-2 hours but AMPK activation effects last 24+ hours. Detectable in urine for ~72 hours. Daily or every-other-day dosing maintains elevated AMPK activity.
Mechanism of Action Aicar 50mg
Aicar is converted to ZMP, an AMP analog that activates AMPK without energy depletion. This triggers PGC-1α → mitochondrial biogenesis, fat oxidation, glucose uptake (via GLUT4), and endurance adaptations identical to chronic exercise training.
How It Works & Key Benefits
Aicar 50mg excels for endurance athletes, recomp phases, or anyone wanting exercise-like benefits with minimal effort.
- Dramatically increases endurance & VO2 max.
- Shifts metabolism to fat burning (even at rest).
- Improves insulin sensitivity & glucose uptake.
- Enhances mitochondrial biogenesis.
- Delivers "exercise mimetic" effects.
- Stacks perfectly with GW-501516, SR-9009.
Who It's For & Product Specifications
Best for endurance athletes, fat-loss seekers, or metabolic optimization; suitable for men and women with medical supervision.
| Substance | 5-Aminoimidazole-4-Carboxamide Ribonucleotide |
|---|---|
| Concentration | 50 mg |
| Form | Vial (requires reconstitution) |
| Pack Size | Vial |
| Half-life | ~1-2 hours (effects 24h+) |
| Primary Use | Endurance, fat loss, metabolic health |
| Manufacturer | Dragon Pharma |
| Brand | Acadesine |
How to Take Aicar 50mg
- Dosage: 25-100 mg/day (most use 50 mg).
- Frequency: Once daily or split pre/post-workout.
- Cycle: 4-8 weeks on, 4 weeks off.
- Administration: Subcutaneous or intramuscular injection.
- Results timeline: Endurance boost in 3-7 days; fat loss in 2-4 weeks.
Popular Stacks
GW-501516 (Cardarine): Ultimate endurance + fat loss combo.
SR-9009 (Stenabolic): 24/7 metabolic acceleration.
Testosterone: Adds anabolic support.
Side Effects & Risk Management
- Mild flushing or warmth — normal AMPK activation.
- Rare: nausea or headache — reduce dose.
- Generally very well-tolerated.
One of the safest performance compounds in research use.
FAQ
Is AICAR safe?
Yes — excellent human trial safety; see Is AICAR Safe.
What is AICAR used for?
Endurance + fat loss (exercise mimetic); see What is AICAR Used For.
How does AICAR promote weight loss?
Activates AMPK → burns fat 24/7; see How Does AICAR Promote Weight Loss.
Does AICAR affect muscle growth?
Indirectly via better training; see Does AICAR Affect Muscle Growth.
Informational only; legality varies by jurisdiction; intended for research purposes. Consult a healthcare professional before use.
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