AICAR (Acadesine) 100 mg is used in research and off-label fitness contexts to enhance endurance, boost fat metabolism, and improve exercise performance. It activates AMPK, mimicking the effects of exercise, and is popular among athletes and bodybuilders for cutting cycles or endurance training optimization.
AICAR activates AMP-activated protein kinase (AMPK), a key regulator of energy homeostasis, increasing fat oxidation, glucose uptake, and mitochondrial biogenesis. This enhances endurance, promotes fat loss, and improves muscle efficiency, with users noticing increased stamina and fat utilization within weeks, depending on dosage and training.
AICAR mimics some exercise effects by activating AMPK, improving endurance and fat metabolism without physical activity, but it doesn't replicate the full cardiovascular, muscular, or psychological benefits of exercise. It's less effective for overall fitness and muscle growth compared to regular training, serving as a supplement rather than a substitute, with effects varying by individual response.
AICAR can be safe when used responsibly under professional guidance, but its safety profile is not fully established due to limited human studies. Potential risks include gastrointestinal distress, hypoglycemia, and long-term metabolic disruption. Regular bloodwork to monitor glucose, liver function, and overall health is advised. Not recommended for beginners or those with metabolic disorders without medical oversight.
Acadesine has a half-life of approximately 1-2 hours, requiring frequent dosing (e.g., daily or twice daily). It remains detectable in the body for about 1-2 days, depending on dosage, metabolism, and testing methods. Bloodwork and professional guidance are advised for precise clearance timelines.
Acadesine activates AMP-activated protein kinase (AMPK), enhancing fat oxidation, glucose uptake, and mitochondrial function to boost endurance and fat metabolism. It mimics exercise-induced energy stress, supporting performance without physical exertion. Effects begin within hours and sustain with consistent use. Users notice metabolic shifts within 1-2 weeks. What doesn't happen: no significant anabolic muscle growth, but cardiovascular monitoring is key.
Aicar 100 mg excels for athletes in endurance or cutting phases, requiring a balanced diet and training to maximize its metabolic and performance benefits.
Best for advanced athletes or researchers seeking endurance and fat loss enhancement; suitable for men and women with medical supervision. Not recommended for beginners or those with metabolic conditions without professional guidance.
| Substance | Acadesine |
|---|---|
| Concentration | 100 mg |
| Form | Vial (requires reconstitution) |
| Pack Size | Vial |
| Half-life | ~1-2 hours |
| Aromatization/Hepatic | Non-applicable / Minimal hepatic |
| Primary Use | Endurance enhancement, fat metabolism |
| Manufacturer | Generic Peptides |
| Brand | Acadesine |
Clenbutaxyl: Amplifies fat loss synergy.
Thyroxyl (T3): Enhances metabolic rate.
Yohimbine: Boosts fat-burning effects.
Cycle Support: Supports cardiovascular health during use.
Aicar 100 mg vs GW501516 (Cardarine): Aicar activates AMPK; Cardarine enhances PPAR-delta for endurance.
Aicar 100 mg vs SR9009: Both boost metabolism; SR9009 (Stenabolic) has a different mechanism.
Aicar 100 mg vs Exercise: Aicar mimics some effects but lacks full exercise benefits.
Consult a professional to ensure safe use and monitor metabolic and cardiovascular health.
What is AICAR used for?
AICAR is used to enhance endurance and fat metabolism; see What is AICAR Used for. It's effective—consult professionals for safe use.
How does AICAR affect the body?
It boosts endurance and fat use via AMPK; see How Does AICAR Affect the Body. Monitor with care—consult professionals.
How does AICAR compare to exercise?
It mimics some exercise effects but isn't a substitute; see How Does AICAR Compare to Exercise. Use with training—consult professionals.
Is AICAR safe?
It can be safe with oversight, but risks exist; see Is AICAR Safe. Consult professionals for monitoring.