Kisspeptin
- Strongly stimulates natural testosterone production.
- Increases LH & FSH within hours.
- Restores libido and sexual function.
- Supports fertility and sperm production.
- No HPTA shutdown — fully physiological.
What is Kisspeptin Peptide Used For?
Kisspeptin 10 mg is used to powerfully stimulate the HPG axis, rapidly raising LH/FSH and testosterone levels. It is the gold-standard peptide for treating secondary hypogonadism, restarting natural production after TRT/PED cycles, restoring libido, and enhancing fertility.
Does Kisspeptin Increase Testosterone?
Yes — very effectively. A single 100–300 mcg injection can increase LH by 300–800% and testosterone by 100–300% within 24–48 hours. Effects are dose-dependent and more physiological than hCG or SERMs.
Is Kisspeptin Safe to Take?
Kisspeptin 10 mg is extremely safe in clinical studies. No desensitization occurs with proper pulsatile dosing. Side effects are rare and mild (occasional flushing or nausea). Human trials up to 72-hour continuous infusion showed no serious adverse events.
How Effective is Kisspeptin?
Extremely effective — considered the most potent natural trigger of the reproductive axis. Studies show it raises testosterone faster and higher than GnRH analogs while maintaining perfect pulsatility. Most men report significant libido and energy improvement within days after starting.
How Long Does Kisspeptin 10 mg Stay in Your System?
Kisspeptin has a plasma half-life of ~4 minutes, but downstream LH/FSH pulses last 2–4 hours and testosterone elevation persists 24–72 hours. Injections are typically 2–3x daily or every other day to maintain stimulation.
Mechanism of Action Kisspeptin 10 mg
Kisspeptin binds to KISS1R receptors on GnRH neurons → massive release of GnRH → pituitary LH/FSH surge → testicular Leydig cell testosterone production. Completely upstream and natural — no suppression, no estrogen conversion issues.
How It Works & Key Benefits
Kisspeptin 10 mg excels for men wanting to restart natural testosterone, preserve fertility on cycle, or overcome low-T symptoms without TRT.
- Strongly stimulates natural testosterone production.
- Increases LH & FSH within hours.
- Restores libido and sexual function.
- Supports fertility and sperm production.
- No HPTA shutdown — fully physiological.
- Stacks perfectly with hCG or enclomiphene.
Who It's For & Product Specifications
Best for men with secondary hypogonadism, post-cycle recovery, or libido/fertility optimization.
| Substance | Kisspeptin-10 (Metastin) | |
|---|---|---|
| Concentration | 10 mg | |
| Form | Vial (requires reconstitution) | |
| Pack Size | Vial | |
| Half-life | ~4 minutes | |
| Primary Use | Testosterone, libido, fertility | |
| Manufacturer | Dragon Pharma | |
| Brand | Kisspeptin |
How to Take Kisspeptin 10 mg
- Dosage: 100–300 mcg per injection, 2–3x daily.
- Frequency: Morning + evening (or pre-bed).
- Cycle: 4–12 weeks, or as needed for PCT/fertility.
- Administration: Subcutaneous injection.
- Results: LH/testosterone spike within hours; libido/energy in days.
Popular Stacks
hCG: Ultimate fertility stack.
Enclomiphene: Combined LH drive.
FSH analog: Full spermatogenesis support.
Side Effects & Risk Management
- Very rare: mild flushing, nausea, or headache.
- No desensitization with proper dosing.
- Extremely well-tolerated in human trials.
One of the cleanest and most physiological peptides available.
FAQ
What is kisspeptin peptide used for?
Natural testosterone & fertility restoration; see What is Kisspeptin Peptide Used For.
Does kisspeptin increase testosterone?
Yes — very strongly and naturally; see Does Kisspeptin Increase Testosterone.
Is kisspeptin safe to take?
Extremely safe in clinical data; see Is Kisspeptin Safe to Take.
How effective is kisspeptin?
Most potent natural GnRH trigger; see How Effective is Kisspeptin.
Informational only; legality varies by jurisdiction; intended for research purposes. Consult a healthcare professional before use.
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